Running back Beanie Wells missed a fourth consecutive day of practice on Friday, casting additional doubt on the chances of him playing at St. Louis on Sunday.
Wells suffered a bruised knee in the final preseason game, and coach Ken Whisenhunt wants to be conservative in deciding when it's safe for Wells to play.
"What concerns me is I don't want this to be something in Week 12, or Week 13 or Week 14 that you're having issues with," Whisenhunt said.
Whisenhunt thinks the Cardinals are deep enough at running back to survive without Wells, who led the team in rushing last year as a rookie despite not starting.
Tim Hightower, the starter, is healthy, and backup LaRod Stephens-Howling is assuming a bigger role in the offense this year. Veteran Jason Wright hasn't practiced this week because of turf toe, but he has enough experience to play well without practicing.
"We've got three running backs I feel are very good ones besides Beanie," Whisenhunt said. "It wouldn't be a stretch to bring Beanie to the game, knowing you could use him if you feel like he couldn't handle it. And if he doesn't, you're still O.K., because you're three-deep at that position."